{"id":13708,"date":"2021-02-19T12:43:36","date_gmt":"2021-02-19T17:43:36","guid":{"rendered":"https:\/\/mdicresource.wpengine.com\/?p=13708"},"modified":"2021-08-02T15:11:36","modified_gmt":"2021-08-02T19:11:36","slug":"parkinsons-patients-tolerance-for-risk-and-willingness-to-wait-for-potential-benefits-of-novel-neurostimulation-devices-a-patient-centered-threshold-technique-study","status":"publish","type":"post","link":"https:\/\/mdic-spi.org\/parkinsons-patients-tolerance-for-risk-and-willingness-to-wait-for-potential-benefits-of-novel-neurostimulation-devices-a-patient-centered-threshold-technique-study\/","title":{"rendered":"Parkinson\u2019s Patients\u2019 Tolerance for Risk and Willingness to Wait for Potential Benefits of Novel Neurostimulation Devices: A Patient-Centered Threshold Technique Study (PCOR Project Aim 2 paper)"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.3&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#005ca8&#8243; min_height=&#8221;96px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_module=&#8221;13944&#8243; saved_tabs=&#8221;all&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_search placeholder=&#8221;BEGIN YOUR SEARCH HERE&#8230;&#8221; button_color=&#8221;#e2a632&#8243; placeholder_color=&#8221;#424242&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; form_field_background_color=&#8221;#FFFFFF&#8221; form_field_text_color=&#8221;#000000&#8243; button_text_color=&#8221;#ffffff&#8221; border_width_all=&#8221;0px&#8221;][\/et_pb_search][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221;][et_pb_fullwidth_post_title author=&#8221;off&#8221; comments=&#8221;off&#8221; featured_image=&#8221;off&#8221; text_background=&#8221;on&#8221; text_bg_color=&#8221;#FFFFFF&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_start=&#8221;#005ca8&#8243; background_color_gradient_end=&#8221;rgba(0,92,168,0.31)&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/mdic-spi.org\/wp-content\/uploads\/2021\/02\/circuitry-header-background-scaled.jpg&#8221;][\/et_pb_fullwidth_post_title][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Patient Introduction for Article&#8221; module_class=&#8221;article-patient-intro&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221;][et_pb_row admin_label=&#8221;Patient Perspective &#8211; Row Toggle&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.7.4&#8243; _module_preset=&#8221;default&#8221;][et_pb_toggle title=&#8221;Patient Introduction&#8221; open=&#8221;on&#8221; open_toggle_text_color=&#8221;#FFFFFF&#8221; icon_color=&#8221;#FFFFFF&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;23px&#8221; _builder_version=&#8221;4.9.10&#8243; _module_preset=&#8221;default&#8221; title_text_color=&#8221;#FFFFFF&#8221; title_level=&#8221;h3&#8243; body_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#85bfd1&#8243; text_orientation=&#8221;left&#8221; border_width_all=&#8221;0px&#8221;]<\/p>\n<p>A growing literature has developed identifying outcomes that matter to patients. The study that these published articles (Aims 1, 2 &amp; 3 of <a href=\"https:\/\/mdic-spi.org\/category\/initiative\/patient-centered-outcomes-research\/\">MDIC\u2019s PCOR project<\/a>) are based on demonstrates an approach to identifying outcomes of medical devices for Parkinson\u2019s disease (PD) that are meaningful to patients and regulators. This approach is of interest to patients who seek to provide input to the design of medical device clinical trials to ensure that what matters to patients is incorporated into study endpoints. Although PD was the disease focused on for this study, the approach can be used to study patient perspectives about other disease or treatment areas. This paper summarizes Aim 2 of the project, describing the results of a survey of Parkinson\u2019s patients focused on their willingness to accept certain trade-offs in the development of a potential new treatment device.<\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.6.1&#8243; _module_preset=&#8221;default&#8221;][et_pb_row _builder_version=&#8221;4.6.1&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.6.1&#8243; _module_preset=&#8221;default&#8221;][et_pb_text admin_label=&#8221;Summary&#8221; _builder_version=&#8221;4.9.10&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<h2>Summary<\/h2>\n<p>Parkinson\u2019s disease (PD) is a neurodegenerative condition causing motor, cognitive, psychological, somatic, and autonomic symptoms. This publication reviews Aim 2 of the project, presenting the process by which PD patients were surveyed to understand the maximum level of risk that patients would accept to achieve the potential benefits of a neurostimulation device. The study\u2019s objective was to understand patient preferences and willingness-to-wait for novel neurostimulation devices among PD patients to inform a model of optimal trial design. The study concluded that patients were willing to wait an average of 4 to 13 years for devices that provide different levels of benefit.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/mdic-spi.org\/wp-content\/uploads\/2021\/02\/Parkinsons-Patients-Tolerance-for-Risk-and-Willingness-to-Wait-for-Potential-Benefits-of-Novel-Neurostimulation-Devices-A-Patient-Centered-Threshold-Technique-Study.pdf&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;Download the Article %91PDF%93&#8243; button_alignment=&#8221;center&#8221; admin_label=&#8221;Button &#8211; Download the Article %91PDF%93&#8243; _builder_version=&#8221;4.9.3&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.8.1&#8243; _module_preset=&#8221;default&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.8.1&#8243; _module_preset=&#8221;default&#8221;][et_pb_text admin_label=&#8221;h5 &#8211; Jump directly to a specific note within the PDF Report:&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<h5>Jump directly to a specific note within the Workshop Summary:<\/h5>\n<p>[\/et_pb_text][et_pb_toggle title=&#8221;CLINICAL&#8221; open=&#8221;on&#8221; admin_label=&#8221;Toggle &#8211; CLINICAL&#8221; _builder_version=&#8221;4.9.1&#8243; _module_preset=&#8221;default&#8221; disabled_on=&#8221;off|off|off&#8221;]<\/p>\n<p><a href=\"https:\/\/mdic-spi.org\/wp-content\/uploads\/2021\/02\/Parkinsons-Patients-Tolerance-for-Risk-and-Willingness-to-Wait-for-Potential-Benefits-of-Novel-Neurostimulation-Devices-A-Patient-Centered-Threshold-Technique-Study.pdf\" target=\"_blank\" rel=\"noopener\">Introduction\u00a0<\/a><\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;REGULATORY DECISION&#8221; open=&#8221;on&#8221; admin_label=&#8221;Toggle &#8211; REGULATORY DECISION&#8221; _builder_version=&#8221;4.9.1&#8243; _module_preset=&#8221;default&#8221; disabled_on=&#8221;off|off|off&#8221;]<\/p>\n<p><a href=\"https:\/\/mdic-spi.org\/wp-content\/uploads\/2021\/02\/Parkinsons-Patients-Tolerance-for-Risk-and-Willingness-to-Wait-for-Potential-Benefits-of-Novel-Neurostimulation-Devices-A-Patient-Centered-Threshold-Technique-Study.pdf\" target=\"_blank\" rel=\"noopener\">Introduction<\/a><\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A growing literature has developed identifying outcomes that matter to patients. The study that these published articles (Aims 1, 2 &amp; 3 of MDIC\u2019s PCOR project) are based on demonstrates an approach to identifying outcomes of medical devices for Parkinson\u2019s disease (PD) that are meaningful to patients and regulators. This approach is of interest to [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":13721,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[7,16,8,32],"tags":[41,62,56],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Parkinson\u2019s Patients\u2019 Tolerance for Risk and Willingness to Wait for Potential Benefits of Novel Neurostimulation Devices: A Patient-Centered Threshold Technique Study (PCOR Project Aim 2 paper) - MDIC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mdic-spi.org\/parkinsons-patients-tolerance-for-risk-and-willingness-to-wait-for-potential-benefits-of-novel-neurostimulation-devices-a-patient-centered-threshold-technique-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Parkinson\u2019s Patients\u2019 Tolerance for Risk and Willingness to Wait for Potential Benefits of Novel Neurostimulation Devices: A Patient-Centered Threshold Technique Study (PCOR Project Aim 2 paper) - MDIC\" \/>\n<meta property=\"og:description\" content=\"A growing literature has developed identifying outcomes that matter to patients. The study that these published articles (Aims 1, 2 &amp; 3 of MDIC\u2019s PCOR project) are based on demonstrates an approach to identifying outcomes of medical devices for Parkinson\u2019s disease (PD) that are meaningful to patients and regulators. 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